The University of Houston’s Hewlett Packard Enterprise Data Science Institute, in collaboration with departments and colleges, leads research, education, and service activities in the broad area of data science and scientific computing and their applications. This includes application areas that are important to the Houston economy: energy and health. Research in data science will range from foundational research in data science and scientific computing to key application areas, including UH Research Thrusts: cyber and physical security, drug development and discovery, sustainable communities and infrastructure and accessible and personalized health care.